Como é a vacina da Covid-19 feita pela UFPR

[{"selector":"#anim-2c54daa9-8468-4cf2-91e4-f8be078ee8ed","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Como é a vacina da Covid-19 feita pela UFPR

[{"selector":"#anim-d35f1445-eca8-4030-a8db-3ffb50df72ae","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2548dd80-e854-462f-bd03-78e3879a8295","keyframes":{"transform":["translate3d(-120.54795%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-86e7638b-a3c2-45f4-a696-aacdc94b2b43","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8ea67db7-6bbd-40df-bbaf-0c8b146de820","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-d9b0786c-dbc6-477c-ab5d-9fcdd25fc4ab [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(-2.321225949375208%, 7.259022360772499%) scale(0.8547008547008547)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":5000,"fill":"forwards"}] A Universidade Federal do Paraná (UFPR) pediu à Anvisa autorização para testar vacina contra Covid-19 em humanos.

[{"selector":"#anim-81601106-fee4-428b-aa49-de528b16ebac","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b90c56fb-c8c7-46fb-a752-b2a0e39eaeb9","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b981006d-4ae1-46ca-bbc9-2a3f700a7d45","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-652977aa-b2e4-4d20-b86b-8f0efd1591d2","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-2fea7322-e1c2-483f-aa94-3ee59f99a2bf","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] A vacina que está em desenvolvimento desde 2020 não depende de insumos importados, o que torna baixo o custo de produção do imunizante.

[{"selector":"#anim-f1aba172-3371-4bf3-aacd-fe1fbef8a129","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1089ffa6-bdee-43e4-93e4-0becd99f9cae","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-98a74e6b-3eda-42b7-8410-4f68483bfb38","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-17633c63-949e-4250-8b22-ddeb3c6732ba","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-60496f09-0dc6-4f3e-84b2-79c11defe470","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] A tecnologia utilizada pelos pesquisadores utiliza partes específicas da proteína que permite a entrada do coronavírus nas células saudáveis.

[{"selector":"#anim-4373e11a-c34c-47bf-815d-eeb0ae13bd73","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a072f20b-b719-4f74-a50e-bd3e2ec54d5a","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7c7351e1-f0bf-4e1e-847e-3ae845607f80","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a0a21a6c-9680-4e89-83bb-5a020b5666a6","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-84e0cd2e-6406-4d1a-971d-92a53befe77e","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Além da proteína, o imunizante usa outro componente inerte ao corpo humano. Trata-se de uma material biodegradável e biocompatível com seres humanos.

[{"selector":"#anim-4a26865a-9d4d-4885-8c9f-418ece0a29a8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fa4155db-6fe9-4c72-bd84-f6c221052687","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5fc281c4-f304-4d83-9d13-48899b8609b6","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bccd348b-34d4-45b9-adcd-4a179202d9f1","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-9896b4ab-1e35-4067-b4cb-835a442aca1c","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Atualmente, o desenvolvimento da vacina está na chamada fase pré-clínica, que é realizada em parceria com o Instituto Carlos Chagas.

[{"selector":"#anim-fb98b784-3f35-4e9e-8afe-358e2f0470b8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4510d9e0-e83e-43c6-940b-1d2894e3368e","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-73e558b2-9070-49e9-815e-31462c7c2772","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4971ddaf-b16d-475f-8d46-85ac55d9363e","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-64080dc9-154a-4bc5-a1e9-a00d792acdf6","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Nesta fase, animais vacinados são expostos ao coronavírus, o que permite verificar a eficácia do imunizante.

[{"selector":"#anim-07a1c05d-0fc7-4e43-9663-c6fddf0c79fc","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8494c186-445a-4ea8-9a9f-f643abf63070","keyframes":{"transform":["translate3d(-120.89042%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a5d1f36f-f882-4f49-a6ed-7fb38512f65c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4104d84a-d6a6-4a45-b11e-865c0a54fc89","keyframes":{"transform":["scale(0.15)","scale(1)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"forwards"}] [{"selector":"#anim-61633db4-4690-4742-a3bf-f38e674f6cc2","keyframes":{"transform":["translate3d(0px, -100.06072%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Após a conclusão, e com autorização da Anvisa, será possível planejar o recrutamento de voluntários para a primeira etapa dos testes com seres humanos.

[{"selector":"#anim-dac34d0f-5f31-4614-b759-d52632a65bb0","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b9965b7c-1137-4e9d-823e-7f9ad407ce29","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-abf5aa4d-55de-4f9f-91e0-e481fedb3069","keyframes":{"opacity":[0,1]},"delay":400,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-20a71319-4d23-476a-b5ca-cc54ccc6be65","keyframes":{"opacity":[0,1]},"delay":400,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d727f3bc-df63-4392-9ccf-b44098eac265","keyframes":{"opacity":[0,1]},"delay":400,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Créditos Apuração: Fabio Calsavara. Imagens: Divulgação/UFPR, Unsplash. Montagem: Caroline do Prado.